OCT imaging is
mainly used in clinical applications rather than others. OCT imaging is used in
imaging retina, macula, and optic nerve in analysing the morphology and changes
in the disease states. Retinal thickness measurement observed by SD-OCT systems
is used to monitor the various states of the disease. The difference between
different holes can distinguished by OCT images and can be diagnosed. Various
clinical applications of OCT images are discussed below.
SD-OCT system is
used to evaluate the choroidal thickness. The choroid in the healthy eye person
is thickest subfoveally and becomes thin nasally. In addition to this choroidal
thickness and age have negative correlation. For example, mean subfoveal
choroidal thickness using Spectralis OCT is 287 ± 76 ?m and using the Cirrus
OCT is 272 ± 81 ?m for the person with age 54 and 34 respectively. Using the
examination of choroidal measurements using SD-OCT diseases can be diagnosed.
Diabetic retinopathy is a main
cause for the visual impairment of the working adults. Delayed choroidal
vascular filling, which manifests as choroidal hypofluorescence on ICG, is
observed in eyes affected with diabetic retinopathy, and correlates with the
severity of disease. Using OCT imaging analysis choroidal thickness of the
eyes, who is affected by diabetic retinopathy can be observed and further can
analyse the severity of the disease.
Inherited retinal diseases
Various features in the retina
of the patient can be evaluated by OCT imaging system. By evaluating the OCT images,
we can observe choroidal blood flow and correlates with the cone function in
eyes affected with retinitis pigmentosa (stated in Scanning Doppler flowmetry
studies). Evaluation of diseases such as retinal dystrophies and retinitis
pigmentosa can be achieved using OCT system. The mean choroidal thickness of
patient with retinitis pigmentosa is 245.6 ± 103 ?m, while for a healthy eye person
is 337.8 ± 109 ?m.
Intraocular tumors in
the choroidal layer can be detected through OCT images. Recent investigations
have showed that delineation of tumor borders, analysis of choriocapillaries and
other blood vessels in the tumors can be observed by OCT imaging system. It
allows to analyse the thickness of choroid layer and detect the lesions in it.