OCT imaging ismainly used in clinical applications rather than others. OCT imaging is used inimaging retina, macula, and optic nerve in analysing the morphology and changesin the disease states. Retinal thickness measurement observed by SD-OCT systemsis used to monitor the various states of the disease. The difference betweendifferent holes can distinguished by OCT images and can be diagnosed. Variousclinical applications of OCT images are discussed below.
Choroidal ImagingSD-OCT system isused to evaluate the choroidal thickness. The choroid in the healthy eye personis thickest subfoveally and becomes thin nasally. In addition to this choroidalthickness and age have negative correlation.
For example, mean subfovealchoroidal thickness using Spectralis OCT is 287 ± 76 ?m and using the CirrusOCT is 272 ± 81 ?m for the person with age 54 and 34 respectively. Using theexamination of choroidal measurements using SD-OCT diseases can be diagnosed. Diabetic retinopathyDiabetic retinopathy is a maincause for the visual impairment of the working adults. Delayed choroidalvascular filling, which manifests as choroidal hypofluorescence on ICG, isobserved in eyes affected with diabetic retinopathy, and correlates with theseverity of disease.
Using OCT imaging analysis choroidal thickness of theeyes, who is affected by diabetic retinopathy can be observed and further cananalyse the severity of the disease. Inherited retinal diseasesVarious features in the retinaof the patient can be evaluated by OCT imaging system. By evaluating the OCT images,we can observe choroidal blood flow and correlates with the cone function ineyes affected with retinitis pigmentosa (stated in Scanning Doppler flowmetrystudies). Evaluation of diseases such as retinal dystrophies and retinitispigmentosa can be achieved using OCT system. The mean choroidal thickness ofpatient with retinitis pigmentosa is 245.6 ± 103 ?m, while for a healthy eye personis 337.8 ± 109 ?m. Intraocular tumorsIntraocular tumors inthe choroidal layer can be detected through OCT images.
Recent investigationshave showed that delineation of tumor borders, analysis of choriocapillaries andother blood vessels in the tumors can be observed by OCT imaging system. Itallows to analyse the thickness of choroid layer and detect the lesions in it.